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Article

Effect of MicroRNA Modulation on Bioartificial Muscle Function

29 Jul 2010

Abstract excerpt

Cellular therapies have recently employed the use of small RNA molecules, particularly microRNAs (miRNAs), to regulate various cellular processes that may be altered in disease states. In this study, we examined the effect of transient muscle-specific miRNA inhibition on the function of three-dimensional skeletal muscle cultures, or bioartificial muscles (BAMs). Skeletal myoblast differentiation in vitro is...

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PMID: 20670163
DOI: 10.1089/ten.tea.2009.0601

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