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The hOGG1 Ser326Cys polymorphism contributes to digestive system cancer susceptibility: evidence from 48 case-control studies.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015

Wang Yang, Gao Xujie, Wei Feng, Zhang Xinwei, Yu Jinpu, Zhao Hua, Sun Qian, Yan Fan, Yan Cihui, Li Hui, Ren Xiubao

Abstract excerpt

The Ser326Cys polymorphism in the human 8-oxogunaine DNA glycosylase (hOGG1) gene had been implicated in cancer susceptibility. Studies investigating the associations between the Ser326Cys polymorphism and digestion cancer susceptibility showed conflicting results. Therefore, a meta-analysis was performed to derive a more precise estimation of the relationship. We conducted a meta-analysis of 48 studies that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25323581
DOI: 10.1007/s13277-014-2710-6

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