Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

USP14 activation promotes tumor progression in hepatocellular carcinoma

21 Sept 2015

Abstract excerpt

To elucidate the molecular mechanisms underlying the pathogenesis and treatment of human primary hepatocellular carcinoma (HCC), it is important to explore novel HCC-associated genes. In the present study, we examined the expression of ubiquitin-specific peptidase 14 (USP14) in patients with HCC using quantitative PCR and immunohistochemical techniques. The expression of USP14 in tumor tissues of patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Peptidase Inhibition and Analysis
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26397990
DOI: 10.3892/or.2015.4296

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

USP14 activation promotes tumor progression in hepatocellular carcinomaPMID 26397990Read ↗

USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axisSemantic proximity Read ↗

Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinomaSemantic proximity Read ↗

USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilizationSemantic proximity Read ↗

Deubiquitinating enzyme USP44 suppresses hepatocellular carcinoma progression through inhibiting Hedgehog signaling and PDL1 expressionSemantic proximity Read ↗

Identification and Validation of Ubiquitin-Specific Proteases as a Novel Prognostic Signature for Hepatocellular CarcinomaSemantic proximity Read ↗

Comprehensive analysis of ubiquitin‐specific protease 1 reveals its importance in hepatocellular carcinomaSemantic proximity Read ↗

Gene Signature and Prognostic Value of Ubiquitin-Specific Proteases Members in Hepatocellular Carcinoma and Explored the Immunological Role of USP36Semantic proximity Read ↗

USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1Semantic proximity Read ↗

Over-Expression of Deubiquitinating Enzyme USP14 in Lung Adenocarcinoma Promotes Proliferation through the Accumulation of β-CateninSemantic proximity Read ↗

The deubiquitinase USP21 stabilizes MEK2 to promote tumor growthSemantic proximity Read ↗

USP15 Represses Hepatocellular Carcinoma Progression by Regulation of Pathways of Cell Proliferation and Cell Migration: A System Biology AnalysisSemantic proximity Read ↗

USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In VitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.