Article
Prevention by alpha-difluoromethylornithine of skin carcinogenesis and immunosuppression induced by ultraviolet irradiation.
Journal of cancer research and clinical oncology - 1 Jan 1991
Gensler H L
Abstract excerpt
Administration of alpha-difluoromethylornithine (DFMO) to mice was found to inhibit both the cutaneous carcinogenesis and the immunosuppression induced by ultraviolet B (UVB) irradiation. BALB/cAnNTacfBR mice were given 1% F2MeOrn in their drinking water throughout the experiment. After 3 weeks,...
Topics
- Animals
- Eflornithine
- Female
- Immunosuppression Therapy
- Mice
- Mice, Inbred BALB C
- Phenotype
- Skin
- Skin Neoplasms
- Spleen
- Ultraviolet Rays
