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Article

Molecular and Cellular Mechanisms of Photocarcinogenesis<sup>†</sup>

16 Nov 2007

Abstract excerpt

Skin cancer constitutes one of the most frequent types of malignancies in humans with rapidly increasing incidences almost worldwide. UVR is an essential risk factor for the development of premalignant as well as malignant skin lesions. In this context UVR can function as a complete carcinogen by inducing "UV signature" DNA mutations and by suppressing protective cellular antitumoral immune responses. UV-induced...

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Identifiers

PMID: 18173698
DOI: 10.1111/j.1751-1097.2007.00231.x

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