Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Influenza A/H1N1/2009 Hemagglutinin Vaccine Produced in Escherichia coli

22 Jul 2010

Abstract excerpt

BACKGROUND: The A/H1N1/2009 influenza pandemic made evident the need for faster and higher-yield methods for the production of influenza vaccines. Platforms based on virus culture in mammalian or insect cells are currently under investigation. Alternatively, expression of fragments of the hemagglutinin (HA) protein in prokaryotic systems can potentially be the most efficacious strategy for the manufacture of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Influenza Virus Research Studies
Share to Transgenic Plants and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20661476
DOI: 10.1371/journal.pone.0011694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Influenza A/H1N1/2009 Hemagglutinin Vaccine Produced in Escherichia coliPMID 20661476Read ↗

Cell-free production of trimeric influenza hemagglutinin head domain proteins as vaccine antigens.Semantic proximity Read ↗

The Receptor-Binding Domain of Influenza Virus Hemagglutinin Produced in <i>Escherichia coli</i> Folds into Its Native, Immunogenic StructureSemantic proximity Read ↗

Efficacious Recombinant Influenza Vaccines Produced by High Yield Bacterial Expression: A Solution to Global Pandemic and Seasonal NeedsSemantic proximity Read ↗

Unique features of a recombinant haemagglutinin influenza vaccine that influence vaccine performanceSemantic proximity Read ↗

Identification and Structural Characterization of a Broadly Neutralizing Antibody Targeting a Novel Conserved Epitope on the Influenza Virus H5N1 HemagglutininSemantic proximity Read ↗

A promoter mutation in the haemagglutinin segment of influenza A virus generates an effective candidate live attenuated vaccine.Semantic proximity Read ↗

Advances in protein subunit vaccines against H1N1/09 influenzaSemantic proximity Read ↗

Addition of N-glycosylation sites on the globular head of the H5 hemagglutinin induces the escape of highly pathogenic avian influenza A H5N1 viruses from vaccine-induced immunitySemantic proximity Read ↗

Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge.Semantic proximity Read ↗

Production of a novel influenza vaccine using insect cells: protection against drifted strainsSemantic proximity Read ↗

Harnessing an RNA-mediated chaperone for the assembly of influenza hemagglutinin in an immunologically relevant conformation.Semantic proximity Read ↗

Critical assessment of influenza VLP production in Sf9 and HEK293 expression systemsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.