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Article

Promotion of colorectal cancer growth and metastasis by the LIM and SH3 domain protein 1.

Gut - 1 Sept 2010

Zhao Liang, Wang Hui, Liu Chao, Liu Yawei, Wang Xiaoyan, Wang Shuang, Sun Xuegang, Li Jianming, Deng Yongjian, Jiang Yong, Ding Yanqing

Abstract excerpt

BACKGROUND: LIM and SH3 protein 1 (LASP-1), initially identified from a cDNA library of metastatic axillary lymph nodes of breast cancer patients, is a specific focal adhesion protein involved in numerous biological and pathological processes. The overexpression of LASP-1 has been described in several types of cancers, but the role of LASP-1 in colorectal cancer (CRC) is unknown. In a previous study, comparative...

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Identifiers

PMID: 20660701
DOI: 10.1136/gut.2009.202739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Promotion of colorectal cancer growth and metastasis by the LIM and SH3 domain protein 1.PMID 20660701Read ↗

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The LIM and SH3 domain protein family: structural proteins or signal transducers or both?Semantic proximity Read ↗

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker proteinSemantic proximity Read ↗

LIM kinase 1 interacts with myosin-9 and alpha-actinin-4 and promotes colorectal cancer progression.Semantic proximity Read ↗

Lasp‐1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domainsSemantic proximity Read ↗

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