Article
Essential role of non-canonical Wnt signalling in neural crest migration.
Development (Cambridge, England) - 1 Jun 2005
De Calisto Jaime, Araya Claudio, Marchant Lorena, Riaz Chaudhary F, Mayor Roberto
Abstract excerpt
Migration of neural crest cells is an elaborate process that requires the delamination of cells from an epithelium and cell movement into an extracellular matrix. In this work, it is shown for the first time that the non-canonical Wnt signalling [planar cell polarity (PCP) or Wnt-Ca2+] pathway controls migration of neural crest cells. By using specific Dsh mutants, we show that the canonical Wnt signalling...
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