Article
Evolutionary dynamics, epistatic interactions, and biological information.
Journal of theoretical biology - 21 Oct 2010
Strelioff Christopher C, Lenski Richard E, Ofria Charles
Abstract excerpt
We investigate a definition of biological information that connects population genetics with the tools of information theory by focusing on the distribution of genotypes found in a population. Previous research has treated loci as non-interacting by making specific approximations in the calculation of information-theoretic quantities. We expand earlier mathematical forms to include epistasis, or interactions...
Topics
- Alleles
- Biological Evolution
- Epistasis, Genetic
- Genetic Fitness
- Genetic Loci
- Genetics, Population
- Humans
- Information Theory
- Models, Genetic
- Population Dynamics
- Time Factors
