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Article

MYBsuppresses differentiation and apoptosis of human breast cancer cells

26 Jul 2010

Abstract excerpt

INTRODUCTION: MYB is highly expressed in estrogen receptor positive (ER + ve) breast tumours and tumour cell lines. We recently demonstrated that MYB is essential for the proliferation of ER + ve breast cancer cells, and have now investigated its role in mammary epithelial differentiation. METHODS: MCF-7 breast cancer cells were treated with sodium butyrate, vitamin E succinate or...

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PMID: 20659323
DOI: 10.1186/bcr2614

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