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Article

FoxM1 Regulates Mammary Luminal Cell Fate

1 Jun 2012

Abstract excerpt

Elevated expression of FoxM1 in breast cancer correlates with an undifferentiated tumor phenotype and a negative clinical outcome. However, a role for FoxM1 in regulating mammary differentiation was not known. Here, we identify another function of FoxM1, the ability to act as a transcriptional repressor, which plays an important role in regulating the differentiation of luminal epithelial progenitors....

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Identifiers

PMID: 22813746
DOI: 10.1016/j.celrep.2012.05.005

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