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Article

Gene expression mediated by cis-acting sequences of the Krüppel gene in response to the Drosophila morphogens bicoid and hunchback.

The EMBO journal - 1 Aug 1991

Hoch M, Seifert E, Jäckle H

Abstract excerpt

The initial expression of the gap gene Krüppel (Kr) occurs in a precisely bounded central region of the Drosophila blastoderm embryo. According to genetic analysis, the spatial limits of the Kr expression domain are controlled by the morphogenetic activities of the anterior organizer gene bicoid (bcd) and the anterior gap gene hunchback (hb). Using gene fusion analysis, we assayed for cis-acting sequences of the...

Topics

Animals
Base Sequence
Binding Sites
DNA
DNA Fingerprinting
Drosophila
Gene Expression Regulation
Molecular Sequence Data
Mutation
Restriction Mapping
Transcriptional Activation

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Identifiers

PMID: 2065664
DOI: 10.1002/j.1460-2075.1991.tb07763.x
PMCID: PMC452917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2065664-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Gene expression mediated by cis-acting sequences of the Krüppel gene in response to the Drosophila morphogens bicoid and hunchback.PMID 2065664Read ↗

cis-acting control elements for Krüppel expression in the Drosophila embryo.Semantic proximity Read ↗

Autonomous concentration-dependent activation and repression of Krüppel by hunchback in the Drosophila embryo.Semantic proximity Read ↗

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