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Article

Drosophila Krüppel protein is a transcriptional repressor.

Nature - 5 Jul 1990

Licht J D, Grossel M J, Figge J, Hansen U M

Abstract excerpt

Krüppel (Kr), one of the zygotically active Drosophila segmentation genes, is expressed in a restricted domain during the blastoderm stage of embryogenesis and is involved in the control of development of the thoracic and abdominal segments of the fly. Kr encodes a polypeptide containing DNA-binding zinc-finger motifs, disruptions of which yield Kr mutants. We have assayed the transcriptional activities of...

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PMID: 2114551
DOI: 10.1038/346076a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Drosophila Krüppel protein is a transcriptional repressor.PMID 2114551Read ↗

Genome-wide mapping of in vivo targets of the Drosophila transcription factor Kruppel.Semantic proximity Read ↗

cis-acting control elements for Krüppel expression in the Drosophila embryo.Semantic proximity Read ↗

Molecular genetics of Krüppel, a gene required for segmentation of the Drosophila embryo.Semantic proximity Read ↗

Krüppel, a Drosophila segmentation gene, participates in the specification of neurons and glial cells.Semantic proximity Read ↗

Krüppel target gene knockout participates in the proper innervation of a specific set of Drosophila larval muscles.Semantic proximity Read ↗

The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor.Semantic proximity Read ↗

Krüppel-homolog, a stage-specific modulator of the prepupal ecdysone response, is essential for Drosophila metamorphosis.Semantic proximity Read ↗

Conserved function of the Krüppel gap gene in the blowfly Lucilia sericata, despite anterior shift of expression.Semantic proximity Read ↗

Gene expression mediated by cis-acting sequences of the Krüppel gene in response to the Drosophila morphogens bicoid and hunchback.Semantic proximity Read ↗

Role of CtBP in transcriptional repression by the Drosophila giant protein.Semantic proximity Read ↗

Transcriptional Profiling of Krüppel-like Factor 4 Reveals a Function in Cell Cycle Regulation and Epithelial DifferentiationSemantic proximity Read ↗

Specific muscle identities are regulated by Krüppel during Drosophila embryogenesis.Semantic proximity Read ↗

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