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Article

Drosophila Krüppel protein is a transcriptional repressor.

Nature - 5 Jul 1990

Licht J D, Grossel M J, Figge J, Hansen U M

Abstract excerpt

Krüppel (Kr), one of the zygotically active Drosophila segmentation genes, is expressed in a restricted domain during the blastoderm stage of embryogenesis and is involved in the control of development of the thoracic and abdominal segments of the fly. Kr encodes a polypeptide containing DNA-binding zinc-finger motifs, disruptions of which yield Kr mutants. We have assayed the transcriptional activities of...

Topics

Animals
Base Sequence
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Juvenile Hormones
Kruppel-Like Transcription Factors
Metalloproteins
Molecular Sequence Data
Mutation
Recombinant Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repressor Proteins

Transcription Factors

Transcription, Genetic

Source

Identifiers

PMID: 2114551
DOI: 10.1038/346076a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2114551-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Drosophila Krüppel protein is a transcriptional repressor.PMID 2114551Read ↗

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Krüppel, a Drosophila segmentation gene, participates in the specification of neurons and glial cells.Semantic proximity Read ↗

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