A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Krüppel and knirps in the early Drosophila embryo.

doi:10.1038/346577a0

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Article

A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Krüppel and knirps in the early Drosophila embryo.

Nature - 9 Aug 1990

Hülskamp M, Pfeifle C, Tautz D

Abstract excerpt

Segmentation of the Drosophila embryo depends on a hierarchy of interactions among the maternal and zygotic genes in the early embryo. The anterior region is organized maternally by the bicoid (bcd) gene product, which forms a concentration gradient in the anterior half of the embryo. The gap gen...

Topics

Animals
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Female
Gene Expression Regulation
Heterozygote
Juvenile Hormones
Morphogenesis
Mutation
Repressor Proteins
Transcription Factors
Transcription, Genetic

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