Article
Maternal cigarette smoking, metabolic gene polymorphisms, and preterm delivery: new insights on GxE interactions and pathogenic pathways.
Human genetics - 1 May 2008
Tsai Hui-Ju, Liu Xin, Mestan Karen, Yu Yunxian, Zhang Shanchun, Fang Yaping, Pearson Colleen, Ortiz Katherin, Zuckerman Barry, Bauchner Howard, Cerda Sandra, Stubblefield Phillip G, Xu Xiping, Wang Xiaobin
Abstract excerpt
Preterm delivery (PTD, <37 weeks of gestation) is a significant clinical and public health problem. Previously, we reported that maternal smoking and metabolic gene polymorphisms of CYP1A1 MspI and GSTT1 synergistically increase the risk of low birth weight. This study investigates the relationship between maternal smoking and metabolic gene polymorphisms of CYP1A1 MspI and GSTT1 with preterm delivery (PTD) as a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
