Article
Tumor-Initiating and -Propagating Cells: Cells That We Would to Identify and Control
1 Jul 2010
Abstract excerpt
Identification of the cell types capable of initiating and sustaining growth of the neoplastic clone in vivo is a fundamental problem in cancer research. It is likely that tumor growth can be sustained both by rare cancer stem-like cells and selected aggressive clones and that the nature of the mutations, the cell of origin, and its environment will contribute to tumor propagation. Genomic instability, suggested...
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