Article
Mitochondrial respiratory dysfunction-elicited oxidative stress and posttranslational protein modification in mitochondrial diseases.
Annals of the New York Academy of Sciences - 1 Jul 2010
Wu Yu-Ting, Wu Shi-Bei, Lee Wan-Yu, Wei Yau-Huei
Abstract excerpt
Pathogenic mutation in mtDNA and mitochondrial dysfunction are associated with mitochondrial diseases. In this review, we discuss the oxidative stress-elicited mitochondrial protein modifications that may contribute to the pathophysiology of mitochondrial diseases. We demonstrated that excess ROS...
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