Article
Toll-like receptor (TLR) and nucleosome-binding oligomerization domain (NOD) gene polymorphisms and endometrial cancer risk.
BMC cancer - 21 Jul 2010
Ashton Katie A, Proietto Anthony, Otton Geoffrey, Symonds Ian, McEvoy Mark, Attia John, Scott Rodney J
Abstract excerpt
BACKGROUND: Endometrial cancer is the most common gynaecological malignancy in women of developed countries. Many risk factors implicated in endometrial cancer trigger inflammatory events; therefore, alterations in immune response may predispose an individual to disease. Toll-like receptors (TLRs) and nucleosome-binding oligomerization domain (NOD) genes are integral to the recognition of pathogens and are highly...
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