Article
Molecular pathogenesis of endometriosis; Toll-like receptor-4 A896G (D299G) polymorphism: a novel explanation.
Genetic testing and molecular biomarkers - 1 Mar 2011
Latha Madhavi, Vaidya Sirisha, Movva Sireesha, Chava Srinivas, Govindan Sujatha, Govatati Suresh, Banoori Manjula, Hasan Qurratulain, Kodati Vijay Lakshmi
Abstract excerpt
BACKGROUND: Endometriosis is a distressing gynecological disorder. Toll-like receptor 4 (TLR4) is specific for recognition of the molecular pattern of gram-negative bacteria. TLR4 is present on the surface of endometrial cells. Their role in the molecular pathogenesis of endometriosis is postulated through a novel explanation. OBJECTIVE: To study the TLR4 A896G polymorphism in cases of endometriosis and age- and...
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