Article
The HepaRG cell line: biological properties and relevance as a tool for cell biology, drug metabolism, and virology studies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Marion Marie-Jeanne, Hantz Olivier, Durantel David
Abstract excerpt
Liver progenitor cells may play an important role in carcinogenesis in vivo and represent therefore useful cellular materials for in vitro studies. The HepaRG cell line, which is a human bipotent progenitor cell line capable to differentiate toward two different cell phenotypes (i.e., biliary-like and hepatocyte-like cells), has been established from a liver tumor associated with chronic hepatitis C. This cell...
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