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Article

Discontinuity and limited linkage in the homologous recombination system of a hyperthermophilic archaeon.

Journal of bacteriology - 1 Sept 2010

Grogan Dennis W, Rockwood Jananie

Abstract excerpt

Genetic transformation of Sulfolobus acidocaldarius by a multiply marked pyrE gene provided a high-resolution assay of homologous recombination in a hyperthermophilic archaeon. Analysis of 100 Pyr(+) transformants revealed that this recombination system could transfer each of 23 nonselected base pair substitutions to the recipient chromosome along with the selected marker. In 30% of the recombinants, donor...

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PMID: 20644140
DOI: 10.1128/JB.00447-10
PMCID: PMC2937427

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Source receipt: pubmed, retrieved 7 Sept 2026.

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