Article
Klotho inhibits growth and promotes apoptosis in human lung cancer cell line A549
19 Jul 2010
Abstract excerpt
BACKGROUND: Klotho, as a new anti-aging gene, can shed into circulation and act as a multi-functional humoral factor that influences multiple biological processes. Recently, published studies suggest that klotho can also serve as a potential tumor suppressor. The aim of this study is to investigate the effects and possible mechanisms of action of klotho in human lung cancer cell line A549. METHODS: In this study,...
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