Article
Adult stem cells exhibit global suppression of RNA polymerase II serine-2 phosphorylation.
Stem cells (Dayton, Ohio) - 1 Sept 2010
Freter Rasmus, Osawa Masatake, Nishikawa Shin-Ichi
Abstract excerpt
Adult stem cells, which are characterized by their capacity for self-renewal and differentiation, participate in tissue homeostasis and response to injury. They are thought to enter a state of relative quiescence, known as reversible cell cycle arrest, but the underlying molecular mechanisms remain poorly characterized. Previous data from our laboratory has shown that housekeeping gene expression is downregulated...
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