Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs1982073 C allele and FGFR2 rs1219648 G allele in North China.

doi:10.1007/s10549-010-1032-7

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Article

Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs1982073 C allele and FGFR2 rs1219648 G allele in North China.

Breast cancer research and treatment - 1 Jan 2011

Chen Xiao-Hui, Li Xiao-Qing, Chen Ying, Feng Yu-Mei

Abstract excerpt

The high morbidity and aggressive behavior of breast cancer are associated with genetic variations. Single nucleotide polymorphisms (SNPs) in many genes have been demonstrated as a risk factor for breast cancer. In this study, we evaluated the association of the SNP rs1982073 (Leu10Pro) in transforming growth factor-beta 1 (TGFB1) gene and the SNP rs1219648 in fibroblast growth factor receptor 2 (FGFR2) gene with...

Topics

Base Sequence
Breast Neoplasms
China
Female
Gene Expression
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Lymphatic Metastasis
Middle Aged
Polymerase Chain Reaction
Polymorphism, Single Nucleotide
Receptor, Fibroblast Growth Factor, Type 2
Risk
Transforming Growth Factor beta1

Source

Open in PubMed

Identifiers

PMID: 20640597
DOI: 10.1007/s10549-010-1032-7

Genes

FGFR2
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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