In vitro enrichment of tumor-initiating cells from human established cell lines.

Abstract excerpt

This unit describes protocols for culturing and subsequently enriching cancer stem cells (CSCs), also referred to as tumor-initiating cells (TICs), from human established cell lines. TICs are thought to display the major cell population in the tumor with the proliferative capacity to seed tumors, implying that they( )are critical in initiating and driving tumorigenesis. The protocols show the methods for...

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