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Article

Massive gene duplication event among clinical isolates of the Mycobacterium tuberculosis W/Beijing family.

Journal of bacteriology - 1 Sept 2010

Domenech Pilar, Kolly Gaëlle S, Leon-Solis Lizbel, Fallow Ashley, Reed Michael B

Abstract excerpt

As part of our effort to uncover the molecular basis for the phenotypic variation among clinical Mycobacterium tuberculosis isolates, we have previously reported that isolates belonging to the W/Beijing lineage constitutively overexpress the DosR-regulated transcriptional program. While generating dosR knockouts in two independent W/Beijing sublineages, we were surprised to discover that they possess two copies...

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Identifiers

PMID: 20639330
DOI: 10.1128/JB.00536-10
PMCID: PMC2937425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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