Bacillus subtilis mutants harbouring a single copy of the rRNA operon exhibit severe defects in growth and sporulation.

doi:10.1099/mic.0.035295-0

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Article

Bacillus subtilis mutants harbouring a single copy of the rRNA operon exhibit severe defects in growth and sporulation.

Microbiology (Reading, England) - 1 Oct 2010

Nanamiya Hideaki, Sato Makiko, Masuda Kenta, Sato Mikiko, Wada Tetsuya, Suzuki Shota, Natori Yousuke, Katano Masato, Akanuma Genki, Kawamura Fujio

Abstract excerpt

The number of copies of rRNA genes in bacterial genomes differs greatly among bacterial species. It is difficult to determine the functional significance of the heterogeneity of each rRNA operon fully due to the existence of multiple rRNA operons and because the sequence heterogeneity among the rRNA genes is extremely low. To overcome this problem, we sequentially deleted the ten rrn operons of Bacillus subtilis...

Topics

Bacillus subtilis
Gene Deletion
Gene Dosage
Mutation
Ribosomes
Spores, Bacterial
rRNA Operon

Source

Open in PubMed

Identifiers

PMID: 20634236
DOI: 10.1099/mic.0.035295-0

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