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Article

Phenotypic characterization and complementation analysis of Bacillus subtilis 6S RNA single and double deletion mutants.

Biochimie - 1 Oct 2015

Hoch Philipp G, Burenina Olga Y, Weber Michael H W, Elkina Daria A, Nesterchuk Mikhail V, Sergiev Petr V, Hartmann Roland K, Kubareva Elena A

Abstract excerpt

6S RNA, a global regulator of transcription in bacteria, binds to housekeeping RNA polymerase (RNAP) holoenzymes to competitively inhibit transcription from DNA promoters. Bacillus subtilis encodes two 6S RNA homologs whose differential functions are as yet unclear. We constructed derivative strains of B. subtilis PY79 lacking 6S-1 RNA (ΔbsrA), 6S-2 RNA (ΔbsrB) or both (ΔbsrAB) to study the physiological role of...

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PMID: 25576829
DOI: 10.1016/j.biochi.2014.12.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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