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Article

Variability in small airway epithelial gene expression among normal smokers.

Chest - 1 Jun 2008

Ammous Zeinab, Hackett Neil R, Butler Marcus W, Raman Tina, Dolgalev Igor, O'Connor Timothy P, Harvey Ben-Gary, Crystal Ronald G

Abstract excerpt

BACKGROUND: Despite overwhelming data that cigarette smoking causes COPD, only a minority of long-term smokers are affected, strongly suggesting that genetic factors modify susceptibility to this disease. We hypothesized that individual variations exist in the response to cigarette smoking, with variability among smokers in expression levels of protective/susceptibility genes. METHODS: Affymetrix arrays and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18339782
DOI: 10.1378/chest.07-2245
PMCID: PMC3632367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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