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Article

Haplotype analysis discriminates genetic risk for DR3-associated endocrine autoimmunity and helps define extreme risk for Addison's disease.

The Journal of clinical endocrinology and metabolism - 1 Oct 2010

Baker Peter R, Baschal Erin E, Fain Pam R, Triolo Taylor M, Nanduri Priyaanka, Siebert Janet C, Armstrong Taylor K, Babu Sunanda R, Rewers Marian J, Gottlieb Peter A, Barker Jennifer M, Eisenbarth George S

Abstract excerpt

CONTEXT: Multiple autoimmune disorders (e.g. Addison's disease, type 1 diabetes, celiac disease) are associated with HLA-DR3, but it is likely that alleles of additional genes in linkage disequilibrium with HLA-DRB1 contribute to disease. OBJECTIVE: The objective of the study was to characterize major histocompatability complex (MHC) haplotypes conferring extreme risk for autoimmune Addison's disease (AD)....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20631027
DOI: 10.1210/jc.2010-0508
PMCID: PMC3050098

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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