Article
The genetics of autoimmune polyendocrine syndrome type II.
Endocrinology and metabolism clinics of North America - 1 Jun 2002
Robles David T, Fain Pamela R, Gottlieb Peter A, Eisenbarth George S
Abstract excerpt
A series of autoimmune disorders, often Addison's disease, type 1 diabetes mellitus, and thyroid autoimmunity, frequently occurs together in patients with the autoimmune polyendocrine syndrome type II (APS-II). The highest risk HLA genotype for Addison's disease, either as a single disease or in APS-II patients, consists of the genotype DR3/4, DQ2/DQ8 with DRB1*0404. As many as 30% of patients with Addison's...
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