Article
The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study.
The Journal of clinical endocrinology and metabolism - 1 Sept 2010
Underwood Patricia C, Sun Bei, Williams Jonathan S, Pojoga Luminita H, Chamarthi Bindu, Lasky-Su Jessica, Raby Benjamin A, Hopkins Paul N, Jeunemaitre Xavier, Brown Nancy J, Adler Gail K, Williams Gordon H
Abstract excerpt
CONTEXT: Peroxisome proliferator-activated receptor gamma (PPARgamma) agonists often cause volume retention and edema. A relationship between PPARgamma and renin may play a role in this process. OBJECTIVE: The aim was to examine the relationship between the PPARgamma gene and plasma renin activity (PRA) levels in human hypertension. DESIGN, PARTICIPANTS, AND MEASURES: A candidate gene association study was...
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