Article
[Genotype and haplotype analysis of peroxisome proliferators activated receptor α gene and the risk of essential hypertension].
Zhonghua yi xue za zhi - 11 Sept 2012
Ding Yi, Guo Zhi-rong, Wu Ming, Zhou Zheng-yuan, Chen Qiu, Yu Hao, Luo Wen-shu
Abstract excerpt
OBJECTIVE: PPARα, which is expressed in the liver, heart, skeletal muscle, and kidney, regulates lipid and lipoprotein metabolism. The aim of this study was to investigate the association between the PPARα gene and essential hypertension (EH) using a haplotype-based cohort study in a Chinese-Han population. METHODS: 820 subjects (270 males, 550 females) were genotyped for the three single-nucleotide polymorphisms...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
