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Effects of Long-Term Culture on Human Embryonic Stem Cell Aging

14 Jul 2010

Abstract excerpt

In recent years, human embryonic stem (hES) cells have become a promising cell source for regenerative medicine. Although hES cells have the ability for unlimited self-renewal, potential adverse effects of long-term cell culture upon hES cells must be investigated before therapeutic applications of hES cells can be realized. Here we investigated changes in molecular profiles associated with young (<60 passages)...

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PMID: 20629482
DOI: 10.1089/scd.2009.0475

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