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Article

Human embryonic stem cells: mechanisms to escape replicative senescence?

Stem cell reviews - 1 Dec 2007

Zeng Xianmin

Abstract excerpt

Human embryonic stem cells (hESCs) are unique in that they can proliferate indefinitely in culture in an undifferentiated state as well as differentiate into any somatic cells. Undifferentiated hESCs do not appear to undergo senescence and remain nontransformed over multiple passages. Culture hESCs maintain telomere length and exhibit high telomerase activity after prolonged in vitro culture. The ability of hESCs...

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Identifiers

PMID: 18026912
DOI: 10.1007/s12015-007-9005-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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