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Article

Roles of the lncRNAs MEG3, PVT1 and H19 tagSNPs in gastric cancer susceptibility.

BMC cancer - 22 Nov 2024

Abdi Esmat, Latifi-Navid Saeid, Kholghi-Oskooei Vahid, Mostafaiy Behdad, Pourfarzi Farhad, Yazdanbod Abbas

Abstract excerpt

BACKGROUND: Improper expression of long noncoding RNAs (lncRNAs) can cause various cancers. Single nucleotide polymorphisms (SNPs) affect the expression and function of several key lncRNAs. We assessed the associations of MEG3, PVT1, and H19 lncRNA polymorphisms with susceptibility to gastric cancer (GC). METHODS: In Ardabil (a high-risk area in North‒West Iran), 795 blood samples were collected from 396 cases...

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Identifiers

PMID: 39578780
DOI: 10.1186/s12885-024-13209-2
PMCID: PMC11583566

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