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Article

Splice form dependence of beta-neurexin/neuroligin binding interactions.

Neuron - 15 Jul 2010

Koehnke Jesko, Katsamba Phinikoula S, Ahlsen Goran, Bahna Fabiana, Vendome Jeremie, Honig Barry, Shapiro Lawrence, Jin Xiangshu

Abstract excerpt

Alternatively spliced beta-neurexins (beta-NRXs) and neuroligins (NLs) are thought to have distinct extracellular binding affinities, potentially providing a beta-NRX/NL synaptic recognition code. We utilized surface plasmon resonance to measure binding affinities between all combinations of alternatively spliced beta-NRX 1-3 and NL 1-3 ectodomains. Binding was observed for all beta-NRX/NL pairs. The presence of...

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Identifiers

PMID: 20624592
DOI: 10.1016/j.neuron.2010.06.001
PMCID: PMC2910870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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