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Article

Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors

6 Jul 2010

Abstract excerpt

The goal of this study was to characterize and classify pulmonary neuroendocrine tumors based on array comparative genomic hybridization (aCGH). Using aCGH, we performed karyotype analysis of 33 small cell lung cancer (SCLC) tumors, 13 SCLC cell lines, 19 bronchial carcinoids, and 9 gastrointestinal carcinoids. In contrast to the relatively conserved karyotypes of carcinoid tumors, the karyotypes of SCLC tumors...

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PMID: 20615970
DOI: 10.1073/pnas.1008132107

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