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Article

Validation of phage display method for protease inhibitor selection using synthetic hybrid peptides.

Combinatorial chemistry & high throughput screening - 1 Nov 2010

de Marco Renato, Azzolini Simone S, Lovato Diogo V, Torquato Ricardo J S, Amino Rogerio, de Miranda Antonio, Tanaka Aparecida S

Abstract excerpt

A recombinant Haematobia irritans irritans trypsin inhibitor (HiTI - Mw 7030 kDa)) phagemid library was constructed and displayed functionally on the tip of the filamentous M13 phage. A combinatorial library of 7.2 x 10(6) mutants was created with HiTI mutations restricted to the P1'-P3' and P5'...

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Identifiers

PMID: 20615196
DOI: 10.2174/138620710792927394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20615196-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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