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Article

Differential effects of acellular embryonic matrices on pluripotent stem cell expansion and neural differentiation.

Biomaterials - 1 Dec 2015

Yan Yuanwei, Martin Lauren M, Bosco Dale B, Bundy Joseph L, Nowakowski Richard S, Sang Qing-Xiang Amy, Li Yan

Abstract excerpt

Extracellular matrices (ECM) derived from pluripotent stem cells (PSCs) provide a unique tissue microenvironment that can direct cellular differentiation and tissue regeneration, and rejuvenate aged progenitor cells. The unlimited growth capacity of PSCs allows for the scalable generation of PSC-secreted ECMs. Therefore, the derivation and characterization of PSC-derived ECMs is of critical importance in drug...

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Identifiers

PMID: 26410789
DOI: 10.1016/j.biomaterials.2015.09.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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