Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta

7 Jul 2010

Abstract excerpt

Imprinted genes play crucial roles in mammalian development and disruption of their expression is associated with many human disorders including tumourigenesis; yet, the actual number of imprinted genes in the human genome remains a matter of debate. Here, we report on the unexpected finding that the chromosome 19 microRNA cluster (C19MC), the largest human microRNA gene cluster discovered so far, is regulated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20610438
DOI: 10.1093/hmg/ddq272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The primate-specific microRNA gene cluster (C19MC) is imprinted in the placentaPMID 20610438Read ↗

Coordinated Expressional Landscape of the Human Placental miRNome and TranscriptomeSemantic proximity Read ↗

Expression and trafficking of placental microRNAs at the feto‐maternal interfaceSemantic proximity Read ↗

Methylation of the C19MC microRNA locus in the placenta: association with maternal and chilhood body sizeSemantic proximity Read ↗

High-throughput miRNA-sequencing of the human placenta: expression throughout gestationSemantic proximity Read ↗

Evolutionary lineage-specific genomic imprinting at the ZNF791 locusSemantic proximity Read ↗

Lineage-specific genomic imprinting in the <i>ZNF791</i> locusSemantic proximity Read ↗

The Role of Cluster C19MC in Pre-Eclampsia DevelopmentSemantic proximity Read ↗

Dissecting Small Noncoding RNA Landscapes in Mouse Preimplantation Embryos and Human Blastoids for Modeling Early Human EmbryogenesisSemantic proximity Read ↗

A novel approach identifies new differentially methylated regions (DMRs) associated with imprinted genes.Semantic proximity Read ↗

Placentas from pregnancies conceived by IVF/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions†Semantic proximity Read ↗

lincRNA RP24-315D19.10 promotes endometrial decidualization via upregulation of hnRNPA2B1Semantic proximity Read ↗

H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.