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Article

Methylation of the C19MC microRNA locus in the placenta: association with maternal and chilhood body size.

International journal of obesity (2005) - 1 Jan 2020

Prats-Puig Anna, Xargay-Torrent Sílvia, Carreras-Badosa Gemma, Mas-Parés Berta, Bassols Judit, Petry Clive J, Girardot Michael, D E Zegher Francis, Ibáñez Lourdes, Dunger David B, Feil Robert, López-Bermejo Abel

Abstract excerpt

OBJECTIVES: To study DNA methylation at the C19MC locus in the placenta and its association with (1) parental body size, (2) transmission of haplotypes for the C19MC rs55765443 SNP, and (3) offspring's body size and/or body composition at birth and in childhood. SUBJECTS AND METHODS: Seventy-two pregnant women-infant pairs and 63 fathers were included in the study. Weight and height of mothers, fathers and...

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PMID: 31554916
DOI: 10.1038/s41366-019-0450-9

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