Article
Methylenetetrahydrofolate reductase 677 C->T polymorphism: a link between birth weight and insulin resistance in obese adolescents.
International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity - 1 Jun 2011
Frelut Marie-Laure, Nicolas Jean-Pierre, Guilland Jean-Claude, de Courcy Genevieve Potier
Abstract excerpt
The goal of this study is to determine whether cardiovascular risk and the methylenetetrahydrofolate reductase 677 C->T polymorphism (MTHFR), an enzyme involved in folate metabolism and in epigenetics, are linked in morbidly obese non-diabetic adolescents. One-hundred and thirteen obese (BMI = 39.1 ± 6.4 kg/m(2)) adolescents aged 14.4 ± 1.5 years were investigated before entering a weight reduction program....
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