Article
Role of genotyping in non-small cell lung cancer treatment: current status.
Drugs - 3 Dec 2011
Bonanno Laura, Favaretto Adolfo, Rugge Massimo, Taron Miquel, Rosell Rafael
Abstract excerpt
Non-small cell lung cancer (NSCLC) is a common malignant disease with an extremely poor prognosis. Chemotherapeutic treatment for advanced disease is currently based on histological subtyping, but recent discoveries of genetic alterations in subsets of NSCLC have already changed clinical practice with regard to Egfr mutations as predictive markers of response to gefitinib and erlotinib. This has also paved the...
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