Article
Characterization of the O-antigen polymerase (Wzy) of Francisella tularensis.
The Journal of biological chemistry - 3 Sept 2010
Kim Tae-Hyun, Sebastian Shite, Pinkham Jessica T, Ross Robin A, Blalock LeeAnn T, Kasper Dennis L
Abstract excerpt
The O-antigen polymerase of gram-negative bacteria has been difficult to characterize. Herein we report the biochemical and functional characterization of the protein product (Wzy) of the gene annotated as the putative O-antigen polymerase, which is located in the O-antigen biosynthetic locus of Francisella tularensis. In silico analysis (homology searching, hydropathy plotting, and codon usage assessment)...
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