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Article

Gene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositis.

The Journal of pediatrics - 1 Oct 2010

Niewold Timothy B, Kariuki Silvia N, Morgan Gabrielle A, Shrestha Sheela, Pachman Lauren M

Abstract excerpt

OBJECTIVE: To detect genetic polymorphisms associated with high serum interferon alpha (IFN-alpha) levels in juvenile dermatomyositis (JDM) and explore interactions in associated polymorphisms. STUDY DESIGN: Eighty-five children of European ancestry with definite/probable JDM were studied. Selected genetic polymorphisms that were associated with high IFN-alpha levels in 12 untreated patients with newly diagnosed...

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Source

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Identifiers

PMID: 20605164
DOI: 10.1016/j.jpeds.2010.04.034
PMCID: PMC2936662

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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