Article
Elevated serum interferon-alpha activity in juvenile dermatomyositis: associations with disease activity at diagnosis and after thirty-six months of therapy.
Arthritis and rheumatism - 1 Jun 2009
Niewold Timothy B, Kariuki Silvia N, Morgan Gabrielle A, Shrestha Sheela, Pachman Lauren M
Abstract excerpt
OBJECTIVE: Interferon-alpha (IFNalpha) has been implicated in the pathogenesis of juvenile dermatomyositis (DM). The aim of this study was to examine serum IFNalpha activity in a cohort of children with juvenile DM to determine relationships between IFNalpha and indicators of disease activity and severity. METHODS: Thirty-nine children with definite/probable juvenile DM were included in the study. Serum samples...
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