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Article

Juvenile dermatomyositis: immunogenetics, pathophysiology, and disease expression.

Rheumatic diseases clinics of North America - 1 Aug 2002

Pachman Lauren M

Abstract excerpt

Data are rapidly accumulating documenting disease susceptibility may be linked to genetic markers (DQA1*0501 or related alleles) which are associated with upregulation of IFN-alpha/beta inducible genes elicited in response to an antigen which may be viral. Continued immune-mediated inflammation, resulting in partial lipodystrophy and pathological calcifications, may be fanned by the increased production of TNF...

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Source

Identifiers

PMID: 12380371
DOI: 10.1016/s0889-857x(02)00013-3

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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