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Article

Abnormal regulation of soluble and anchored IL-6 receptor in monocytes from patients with essential thrombocythemia.

Experimental hematology - 1 Oct 2010

Goette Nora P, Lev Paola R, Heller Paula G, Glembotsky Ana C, Chazarreta Carlos D, Salim Juan P, Molinas Felisa C, Marta Rosana F

Abstract excerpt

OBJECTIVE: In a previous study, we found increased plasma soluble receptor for interleukin-6 (sIL-6R) levels in patients with essential thrombocythemia (ET) that could promote megakaryopoiesis through IL-6 binding and further interaction with the signal transducer gp130. Here we have searched for the cell source of sIL-6R within mononuclear cells in these patients and the underlying abnormalities involved in its...

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Identifiers

PMID: 20600579
DOI: 10.1016/j.exphem.2010.06.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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