Article
Induction of CD4(+)CD25(+) T regulatory cells with CD103 depletion.
The Journal of surgical research - 1 Sept 2010
Zikri Nancy N, Schumer Erin, Wang Jiao-Jing, Gaughan Alice, Hadley Gregg A, Moffatt-Bruce Susan D
Abstract excerpt
BACKGROUND: M290SAP, a murine CD103 antibody conjugated with the immunotoxin saporin, has been found to induce the indefinite acceptance of transplanted pancreatic islets in mice. We sought to understand the underlying mechanism of this alloacceptance, particularly with respect to the CD4 CD25 T...
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